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We expected that hetNOE, which provides information on protein flexibility, could identify key residues that directly participate in the interaction by comparing the values of the apo- and FHD-bound states

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However, in a single case report of a 7.8 kg terrier mixed breed dog with compulsive disorder, five months of treatment with 5 mg melatonin twice daily along with a combination of cannabinoids and behavioral therapy reduced compulsive behavior and led to easier management by the owner

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