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A clinical study has demonstrated that 11CGln is well tolerated by patients with metastatic colorectal cancer (CRC) and can be visualized noninvasively in multiple organs, including the lungs, brain, and bones (75)

For Prx1, it remains to be demonstrated to what extent hyperoxidation occurs under normal physiological conditions in yeast cells grown in standard laboratory conditions

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However, unlike mGluR5 in Group I, activation of mGluR7 in Group III reduced NMDA-mediated currents and NR1 surface expression in rodent basal forebrain cholinergic neurons through the regulatory mechanism of cofilin (CFL)

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