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Peripheral venous blood samples were drawn after overnight fasting for 12 h

Platelets: at the nexus of antimicrobial defence

[PubMed: 2590068] 23

However, its successful application will require further elucidation of TREM biology in humans, regarding the cell-type specificity of TREM expression (e.g., in astrocytes, oligodendrocytes, and neurons), species differences between humans and mice, immature metabolic and mitochondrial features of in vitro culture (e.g., BV and iPSC-derived cells), early-onset or late-onset, and the temporal dynamics of disease progression with senescence

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