One placebo-controlled trial, called ATTAIN-MAINTAIN, followed adults who had previously completed the SURMOUNT-5 obesity trial, a randomized controlled study evaluating whether tirzepatide, the active ingredient in Zepbound, led to greater body weight reduction versus semaglutide in adults with obesity
Type 2 diabetes was included as a positive control (107,133 cases, 656,672 controls)
If you're having surgery, it's essential to let your anaesthetist know you're on a GLP-1 medication, as they slow down digestion and may increase your risk of complications under anaesthetic
It features a lactam bridge cyclization between Aspartic Acid and Lysine residues, which significantly enhances its stability against enzymatic degradation compared to linear peptides
How to Reset Your Tirzepatide Injection Schedule After a Missed Dose The simplest approach is to treat the one-day-late injection as your new on-time dose