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This process leads to the activation of macrophages, the secretion of inflammatory factors, and ultimately, inflammation in cells such as Kupffer cells, as well as hepatocytes, which produce significant amounts of cytokine, particularly TNF- and IL-6 (Allam et al

They are commonly found in fruits, vegetables, and certain beverages like tea

But step therapy can potentially harm a patient and make treatment longer and more expensive if an insurer first requires a treatment not recommended by the patients physician

Cells 11 , 1553 (2022)

You can also report suspected adverse reactions to the FDAs MedWatch Program at 1-800-FDA-1088 or at www.fda.gov/medwatch