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Medicine 100:e26289

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In general, successful and sustained weight loss has been correlated with the following: Eating a low-calorie diet that is High in fiber High in low-density foods such as fruits and vegetables Moderate-to-high in protein Low in fat Avoiding sweetened drinks Avoiding refined carbohydrates Eating breakfast Avoiding nighttime eating Having regular daily meals Avoiding snacks Engaging in regular exercise Getting adequate sleep (and maintaining a healthy circadian rhythm) Self-monitoring body weight Receiving support from those close to you Healthy Stress Management Medical Approaches to Weight Loss The mainstay of weight loss therapy is calorie reduction and exercise

The c1 = GRID map is represented as mesh (orange) and contoured at 2.5 kcal mol 1