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Supports preclinical study of systemic copper-peptide administration, complementing the more common topical and injectable copper-peptide research models

Food and Drug Administration (FDA) for medical use

Nuclear IGF-IR regulates gene expression While IGF-IR is usually localized at the plasma membrane in normal cells, it often translocates into the cytoplasm and nucleus in cancer cells even though it does not have the nuclear localization signal [78,79,80]

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It is therefore plausible to suggest that deficiencies in vitamin D may play a contributory role in the aetiology of OCD by interfering with the pathways of serotonin and catecholamine synthesis