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Subsequently, we used Pomc -hrGFP mice to perform whole-cell patch-clamp recordings of fluorescently labeled POMC neurons from acute hypothalamic slices that contained areas of the ARH (Fig

Its relevance to women's health crystallised with the finding that MOTS-c levels decline with age and estrogen depletion correlating directly with reduced skeletal muscle insulin sensitivity and visceral adiposity in postmenopausal women