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So, heres what the journey on Mounjaro typically looks like - Starts at 2.5mg for the first 4 weeks Increases by 2.5mg every 4 weeks as tolerated: 5mg, 7.5mg, 10mg, 12.5mg, up to 15mg maximum Most people reach their effective maintenance dose between 7.5mg and 12.5mg You may experience some side effects like nausea, constipation and some fatigue

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By contrast, knockout of Gipr in GABAergic neurones did not prevent the ability of GIPR antagonists to reduce food intake 6