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Ongoing phase 3 trials, PROCORNAC (NCT06956482) and NACAH (NCT03069300), are evaluating whether prolonged NAC therapy, with or without GC, improves outcomes [55,56]

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In vitro studies have shown increased collagen I and III gene expression and protein production in fibroblast cultures treated with GHK-Cu, with effects observed across a range of nanomolar to low micromolar concentrations

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