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doi:10.1016/j.bioorg.2021.105152

Moreover, such a small molecule could serve as a tool compound to interrogate the function of the ADP-ribosyltransferase tankyrase, which is proposed to expel TRF1 from shelterin, thereby promoting telomere extension 18,19,20,21

These medications can be prescribed by a licensed clinicianobesity specialist, general practitioner (MD, DO), endocrinologist, nurse practitioner, or physician assistantwhether in person or online

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(5) Research has shown that by preserving nicotinamide from NNMT-mediated degradation, the compound may enhance NAD+ synthesis through the salvage pathway