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Additional T-lymphocytes could modify the dysfunctional interaction between host astrocytes, microglia, and motor neurons

However, the list includes an S0 category for pharmacological substances that are not addressed elsewhere and have no current approval by a governmental regulatory health authority for human therapeutic use

166 , A626 (2019)

The crossover trial by Tempesta et al 21 was evaluated using the RoB 2 crossover tool, and judgments were consistent with other RCTs, showing some concerns in the randomization and measurement domains