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doi: 10.1177/1535370219830997 16 NakataTMatsuiTKobayashiKKobayashiYAnzaiN
Biochem Biophys Res Commun 482:980986 Shao S, Wang GL, Raymond C et al (2017) Activation of sonic hedgehog signal by purmorphamine, in a mouse model of Parkinsons disease, protects dopaminergic neurons and attenuates inflammatory response by mediating PI3K/AKt signaling pathway
When combined with Retatrutides aggressive weight loss, this preservation effect becomes critically important for body composition outcomes
Briefly, mice were anaesthetised with isoflurane (3% induction, 1.52% maintenance) given at 1 L/min O2 using TEC 3 Isoflurane Vaporiser (98723N, +Mediquip LTD)
Only about 30 humans have ever been studied, all by one doctor, with no control groups
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