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doi: 10.3389/fphar.2024.1491249 Received 04 September 2024 Accepted 14 November 2024 Published 02 December 2024 Volume 15 - 2024 Edited by Anna Maria Giudetti, University of Salento, Italy Reviewed by Daniele Vergara, University of Salento, Italy Azza Awad, Al-Azhar University, Egypt Updates Copyright 2024 Mahmoud, Elshazly, El-shaarawy, Zaitone, Aldahish, Ahmed, Fawzy, Aloyouni, Abed, Saeedi and El-Sayed

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This is related to its promotion of SOD and GSH activity, upregulation of GPX4, SLC7A11, and SLC3A2 expression, reduction of malondialdehyde content and iron concentration, as well as downregulation of TFR1 expression