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PX-12 inhibits the growth of hepatocelluar carcinoma by inducing S-phase arrest, ROS-dependent apoptosis and enhances 5-FU cytotoxicity

2023 Feb Mohammad Hassan Sohouli, Mehdi Mehdinezhad Roshan, Olowoselu F Olusola, Somaye Fatahi, Hamid Reza Omidi, Parastoo Sharifi, Azita Hekmatdoost, Emad Kutbi, Ahmed Abu-Zaid

Moreover, these HLCs displayed significant CYP450 metabolic activities for CYP3A4, CYP2C9, and CYP2D6, similar to PHs