Another investigation by Rahmanian-Devin et al
Look for HPLC purity above 98 percent, mass spectrometry confirmation of the correct molecular weight, endotoxin testing below 1 EU per mg, and sterility testing if the product is injectable
Research suggests the risk may increase with longer duration of use, and certain anatomical features of the eye also play a role
These conditions digestive conditions, such as Crohns disease and ulcerative colitis autoimmune conditions, such as celiac disease and type 1 diabetes genetic conditions, such as inherited intrinsic factor deficiency and inherited transcobalamin deficiency chronic pancreatic disease pernicious anemia vitiligo Other factors that may lead to a vitamin B12 deficiency can include drinking excessive amounts of alcohol or using certain drugs, such as some heartburn medicines and metformin
There are also many products on the market that have been tested and licensed by the Drug Administration - Ministry of Health to treat certain skin conditions, such as hyperpigmentation (which darkens the skin) and facial melasma (causing patches on the face)