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We also often see these medications used to treat obesity or aid weight loss

PHARMACOLOGY AND MODE OF ACTION In order to appreciate the mechanism associated with the DPP-4 inhibitors, we must understand the normal function of incretin hormones

Administered subcutaneously as an injection under the skin, it should be used in conjunction with a reduced-calorie diet and increased physical activity

In 1987, researchers identified GLP-1 as a second incretin hormone derived from the transcription product of the proglucagon gene, which is cleaved differently depending on the tissue

Doses as high as 2 mg (2,000 g) daily by mouth or 1 mg monthly by intramuscular (IM) injection have been used to treat pernicious anemia without significant side effects (136)