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Although we used a mild STZ-induced diabetic mouse model that mimics certain aspects of type 2 diabetes, the inclusion of additional insulin-resistant or diet-induced models in future studies could enhance generalizability

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In practice, that often looks like this: Another important detail is that escitalopram has also shown broad efficacy across doses in a meta-analysis that included 1,061 escitalopram-treated patients and 537 placebo patients , with statistically significant differences on the Liebowitz Social Anxiety Scale at 5 mg, 10 mg, and 20 mg , supporting a real medication effect rather than a chance finding, according to this meta-analysis on PubMed