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We expected that patients taking the GLP-1s for obesity may have a lower cost of care and improved medical outcomes as we presumed that the weight loss could have led to a decrease in the frequency of office/hospital visits and/or the use of drugs for treatment of conditions such as hypertension, high cholesterol and osteoarthritis

This creates a self-targeting effect in the tissue that needs intervention most

Dietary L-carnitine supplementation modifies blood parameters of mid-lactating dairy cows during standardized lipopolysaccharide-induced inflammation

Bibbins-Domingo, K

Although the reasons for the variation are still unclear, this might be due to several differences in the individual study design and patient characteristics rather than drug effect [21]