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5.2 Modulators of cGAS The exploration of engineering and delivery mechanisms for modulators targeting cGAS, aimed at immunotherapy for RA, has been conducted in recent studies (71, 101)

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Under our experimental conditions, the total NAD + -GDH deaminating reaction activity was very low and did not notably alter in response to changing ammonium concentrations (Figure 2D) nor to prolonged ammonium starvation conditions (Table 1)

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