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This precautionary approach, while not a labeled restriction, represents good clinical practice

Because of the unknown potential for serious adverse reactions in the breastfed infant due to the possible accumulation of salcaprozate sodium (SNAC), an absorption enhancer in Semaxen, from breastfeeding and because there are alternative formulations of Semaglutide that can be used during lactation, advise patients that breastfeeding is not recommended during treatment with Semaxen

This enzyme has been reported to increase the rate of reaction between glutathione and free radicals, particularly toxic hydrogen peroxide [22]