TfR mediates the delivery of iron to the bloodbrain barrier and intracellular trafficking of the iron-binding protein transferrin

The DIX domains and axin, GSK-3, and Disheveled (Dvl) are key players in the -catenin destruction complex, thereby determining the interaction of -catenin with the transcription factor TCF and, thus, the expression of the Wnt target genes ( The -catenin/E-cadherin complex is the key component of adherens junctions (AJs), which stabilizes cellcell junctions, provides cellcell adhesion, and binds -catenin with the actin cytoskeleton ( Therefore, dysfunctions in AJs and TJs may cause aberrations in cellcell adhesion and the actin cytoskeleton ( Pseudomonas aeruginosa , one of the bacteria involved in CFAS-D ( Importantly, our MCODE analysis revealed another highly significant molecular complex in the CFAS-D network comprising the hydrogen peroxide metabolic process, amine oxidase reactions, and the -catenin degradation pathway, indicating that interactions between those factors are involved
Liquids 5.2.1.2
Sections were stained with 2% uranyl acetate, and lead citrate
10.1136/bmj.315.7109.629 28 EsmailyH.SahebkarA.IranshahiM.GanjaliS.MohammadiA.FernsG.et al (2015)