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Prog Neurobiol

Another has perfectly normal hunger but a metabolic rate that runs unusually low, an insulin response that turns every carbohydrate into stored fat with ruthless efficiency, and a body that defends a higher set point with hormonal countermeasures every time he tries to lose weight

Ensure adequate protein intake (0.8-1.2 g/kg daily), maintain gradual weight loss of 1-2 pounds weekly when possible, work with a healthcare provider to screen for nutritional deficiencies (especially iron), and stay well-hydrated throughout treatment

Options include other GLP-1 agonists, different diabetes meds, and diet and exercise plans

If additional glycemic control is needed after at least 4 weeks on the: 0.5 mg dosage, the dosage may be increased to 1 mg once weekly