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Dyslipidemia, particularly elevated oxidized LDL (oxLDL), contributes to ROS production by interacting with the lectin-like oxLDL receptor (LOX-1) on dorsal root ganglion neurons and activating NAD(P)H oxidase

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Furthermore, different 2,2-dihydroxybenzophenones and their carbonyl N-analogs showed distinct GSTA1 and GSTP1 isozymes inhibition specificity, with disubstituted benzophenones exhibited a minimal inhibition to GSTP1, whereas the inhibition potency to GSTA1 was still adequate [200]

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