A 2015 permeation study confirmed near-zero transdermal delivery through untreated skin (Li et al., 2015)
domestica leaves during prolonged exposure to heat stress
In combination with a healthcare provider the goal is to find an effective dosage instead of simply the maximum possible dosage
However, it's important to note that the use of Melanotan II for this purpose is controversial and not approved for human use in many countries due to safety concerns
Int J Cancer 142(3):607617 Jingushi K, Uemura M, Nakano K, Hayashi Y, Wang C, Ishizuya Y, Yamamoto Y, Hayashi T, Kinouchi T, Matsuzaki K, Kato T, Kawashima A, Ujike T, Nagahara A, Fujita K, Ueda K, Tsujikawa K, Nonomura N (2019) Leukocyte-associated immunoglobulin-like receptor 1 promotes tumorigenesis in RCC