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Some research investigates transdermal delivery of small-molecule GLP-1 receptor agonists or modified peptides, but these remain in early development stages

Below are the doses studied: Weekly injection: 1 mg 3 mg 6 mg 9 mg 6/9 mg (dose escalation) 3/6/9 mg (dose escalation) Some participants followed a step-up dosing schedule, meaning their dose was gradually increased over time

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Finney JL (1982)