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A retrospective cohort study using real-world data from 1845 elderly patients with T2DM found that GLP-1 RAs use was associated with a significantly lower risk of developing OP, even after adjusting for multiple confounders including age, sex, BMI, smoking, and antihypertensive use

These are uncommon but may include mild diarrhoea or skin reactions (such as acneiform eruptions) based on case reports

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[21] [22] Clinically, certain GLP-1 agonists have demonstrated cardiovascular benefits