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In 2017, subcutaneous semaglutide was the most effective of all GLP-1 medications for lowering A1C: at 40 weeks, patients had a -1.5% A1C reduction using subcutaneous semaglutide vs

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doi:10.1124/jpet.105.084533 Pires DA, Marques PE, Pereira RV, David BA, Gomides LF, Dias AC, Nunes-Silva A, Pinho V, Cara DC, Vieira LQ, Teixeira MM, Menezes GB (2014) Interleukin-4 deficiency protects mice from acetaminophen-induced liver injury and inflammation by prevention of glutathione depletion