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Ophthalmological evaluation before starting GLP-1s has been suggested but is not currently required

Modern pharmacological studies have reported that tetramethylpyrazine (TMP), an active metabolite in Ligusticum chuanxiong , possesses various physiological functions, including antioxidant capabilities, anti-inflammatory actions, anti-apoptotic characteristics, the ability to regulate autophagy, vasodilatory functions, modulation of angiogenesis, inhibition of mitochondrial damage, safeguarding of endothelial cells, and mitigation of vascular smooth muscle cell proliferation and migration, and also offers neuroprotective benefits (Lin et al., 2022)

These cases have included drug-induced injuries to the esophagus, stomach, and small intestine

Changes in brain metabolites related to stress resilience: metabolomic analysis of the hippocampus in a rat model of depression

Role of P53 and P21 Waf1/Cip1 in Senescence-Like Terminal Proliferation Arrest Induced in Human Tumor Cells by Chemotherapeutic Drugs