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This includes genetics, environment, and lifestyle

This analysis further assessed whether the increase in DRP was a GLP-1 specific effect, or rather caused by a robust and early glucose lowering as suggested by several other studies, where acute and large reductions in glucose concentrations may initially and transiently worsen DRP, yet prevent or delay onset or progression of DRP in the long term (123128)

Some of the most common are: Anemia, when the body does not have enough red blood cells Thyroid issues Depression Any chronic condition or injury that causes persistent pain Sleep disorders Addisons disease, when the adrenal glands dont produce enough hormones Eating disorders Viral illnesses, like the flu or COVID-19 Diabetes Kidney disease Liver disease A healthcare provider can diagnose the underlying cause of fatigue, whether its semaglutide or another underlying condition

Meier J, Bauer R, Blicher TM