While semaglutide may cause side effects, the risk of a reaction due to sulfa ingredients is not present because it does not contain any sulfonamides
We are encouraged by the robust reductions in liver fat content and abdominal adipose tissue observed with all three doses of tirzepatide in this population of adults with type 2 diabetes and elevated liver fat content. SURPASS-3 was a 52-week, multi-center, randomized, phase 3, open-label trial evaluating the efficacy and safety of tirzepatide compared to titrated insulin degludeci in adults with type 2 diabetes who have inadequate glycemic control on stable doses of metformin with or without an SGLT-2 inhibitor
In a study in 2,424 middle-aged and older adults in China, eating a healthy plant-based diet (eg, generally a Mediterranean-style diet rich in plant fibers, whole grains, vegetables, and minimally processed food) was associated with better sleep quality, while eating an unhealthy plant-based diet (ie, highly processed) was linked to poorer sleep quality
Gut Microbe-Generated Trimethylamine N-Oxide From Dietary Choline Is Prothrombotic in Subjects. Circulation 135:16711673
These include lifestyle modification requirements (69%), trialing lower-cost medications first (63%) and limiting therapy duration (63%)
