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Se adquiere comiendo determinados alimentos, sobre todo de origen animal y puede sintetizarse en hgado y rin a partir de los aminocidos esenciales L-Lisina y L-Metionina as como vitamina C, B6, niacina, hierro y diversas enzimas

(32(2)):288-293 doi:10.1097/MEG.0000000000001748

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It reduces iron from the ferric to the ferrous state in the intestine to allow absorption, is involved in the transfer of iron from plasma transferrin to liver ferritin, and regulates iron distribution and storage by preventing the oxidation of tetrahydrofolate