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This technique is derived from 60 years of formulation method research

Weve seen researchers misplace a decimal and end up with a solution thats ten times too strong or too weak

Hydroquinone is an active ingredient that can only be used for a short amount of time, typically up to 3 -4 months at a time 14

We hypothesize that (i) the slow inhibition observed in the biochemical assay with the recombinant protein with some of the compounds is due to their preferential binding to a slowly populated conformer of the NADP + -TGR(H) complex and (ii) this conformer is already populated in the worm cell interior accounting for the more rapid inhibition of TGR observed in ex vivo worms with the slow inhibitors

The first site interacts with the GSH moiety of glutathionylated disulfide substrates