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The aforementioned results indicated that in the ovaries, CXCL10 could bind to IL18R1 to activate downstream p-P65 IFN signaling, which subsequently promoted the transformation of macrophages into pro-inflammatory type I macrophages (Fig

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Sterile water is appropriate when benzyl alcohol must be avoided or when the entire vial will be used in a single session

Transplanting unmodified bone marrowderived cells into 70-day-old SOD1 G93A mice resulted in spinal cord engraftment but had no effect on mouse survival ([26, 138]