does glp 1 do more than suppress appetite 504: Adult Eating Disorders in the GLP-1 Era GLP-1 Medications for Weight Loss:

119,123 However, given the dynamic environment of the knee and the low residence time of small molecules in the synovial space, delivery and retention of molecules to positively impact cartilage regeneration before being cleared remains a challenge

In clinical trials of Ozempic and Wegovy, nausea was reported in: 15.8% of people taking a 0.5 milligram (mg) dose 20.3% of people taking a 1 mg dose 44% of people taking a 2.4 mg dose Nausea is a common side effect of semaglutide, but its also seen with other similar medications in the GLP-1 receptor agonist class

What should we consider before combining these two

Potential for desensitization with long-term use

At 2.5mg/mL, a 0.5mL syringe covers doses up to 1.25mg (50 units)