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Ozempic has a long half-life of approximately one week, which is why it is administered as a once-weekly subcutaneous injection

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Blood samples Blood samples were collected at three timepoints using Monovettes (Sarstedt, Nmbrecht, Germany): fasting state (T0, SI1) to determine the concentrations of ghrelin, glucose, insulin, triglycerides, testosterone, progesterone, and estradiol, 60 min after a standardized breakfast (T2) to determine meal-induced changes in ghrelin, glucose, and insulin, and at the end of the session (5-10 min after the end of scan, T3) to determine ghrelin and triglycerides