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GLP-1 reduces blood sugar by suppressing glucagon, a hormone that signals the liver to release stored glucose into the bloodstream

others plateau at 5% without dose adjustment or medication switching

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In a mouse model of diet-induced MASH, treatment with semaglutide resulted in histological improvements in steatosis, inflammation, and fibrosis in liver compared to baseline, which was associated with body weight loss, intermittent periods of reduced food intake, and improvements in relevant biomarkers

So if that is true, considering the large number of patients that are now taking Ozempic