glutathione peroxidase chemical structure The family: Discoveries and mechanism AZD5904 | Glutathione Peroxidase Inhibitor

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Data confirmed the upregulation of Ggt1, Sepw1, and Muc1 genes in 3D spheroids and suggested that, since GGT1 provides substrates for glutathione synthesis, which is utilized as cofactor of both GPX4 and Selenoprotein W, lung CSCs may be protected from ferroptosis by the activation of a GSH-dependent antioxidant mechanism