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doi: 10.1007/S10926-022-10075-2 236 BarbaraCClavarioPDe MarzoVLottiRGuglielmiGPorcileAet al

Poor candidates include patients with uncontrolled medical conditions or active body dysmorphic disorder

2) Provides Antioxidant Protection Oxidative stress can trigger excess melanin formation and accelerate skin dullness

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Loss of ER redox homeostasis can lead to ER stress and induction of the unfolded protein response (UPR) which, if severe enough will trigger cell death via the apoptotic pathway