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How Does GLP-3 Compare to Tirzepatide and Semaglutide

A 2023 study revealed that theres a slightly increased risk for intestinal obstruction (when your intestines cant contract, making it hard to get rid of waste), because semaglutide slows down food as it travels through your digestive system (17)

Hierarchy of Evidence: Level D (Pre-clinical animal models)

In a previous cohort study comparing GLP-1RAs with anti-obesity medications bupropion-naltrexone in patients with obesity who had no T2DM [45] showed an increased risk of bowel obstruction

Semaglutide costs Brand-name semaglutide (Wegovy for weight loss, Ozempic for diabetes) costs significantly more