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Oxidative stress sensor Keap1 functions as an adaptor for cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

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In HT patients, primary hypothyroidism occurs after the destruction of CD8 + and MF directly or with the help of released cytokines by NK-cells in ADCC (antibody-dependent cell-mediated cytotoxicity) of a sufficient number of follicular cells that produce TG (19, 20, 28)

Lancet 391, 26072618