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Glutamine also contributes to maintaining acid-base balance by its ability to produce ammonium ions, a typical weak base [82]

Notably, we found age-dependent brain atrophy in GCLC floxed X CaMKII-Cre mice (GCLC-KO) mice but not in wild-type (WT) mice (Fig

Lipotropic agents: Commonly methionine (an essential amino acid), inositol (a carbohydrate compound), and choline (a nutrient involved in lipid transport)

At later stages of AD, there is a noticeable reduction in NCOA4 levels in the grey matter, which supports the previously proposed hypothesis that long-term NCOA4 decrease makes cells more susceptible to ferroptosis [40]