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Sohita Dhillon is a salaried employee of Adis/Springer, is responsible for the article content and declares no relevant conflicts of interest

(AP) What to expect when starting a GLP-1 Patients who start GLP-1s for weight loss may first notice they feel more full after eating and think less about food, sometimes called food noise. Nausea, vomiting, bloating, diarrhea and constipation are normal in these first few days and after a dosage increase

Track waist circumference, progress photos, how clothing fits, energy levels throughout the day, sleep quality, blood work improvements (A1C, lipids, liver enzymes), and appetite patterns and food relationships

The conversion between semaglutide and tirzepatide requires careful dose adjustment, so this is not a switch to make without medical guidance

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