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But scientists who carefully measure overall GH production report that it rises during childhood, peaks during puberty, and declines from middle age onward

Monitoring Your provider may recommend periodic blood work (e.g., vitamin B12 levels, liver function tests) to assess effectiveness and detect potential issues

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The double-blind multicenter phase 3 trials STEP 1, 3, 4, 5 were conducted in adults (mean age 46.247.3 years), mostly females, with obesity or overweight with 1 weight-related complication (mean BMI 37.838.4 kg/m 2 ) and aimed to demonstrate the superiority of semaglutide 2.4 mg over placebo in BW lowering at 68 or 104 24 weeks as an adjunct to diet and physical activity 23