Second, it is able to induce the combination of ,-unsaturated ketones and GSH through the nucleophilic addition reaction, depleting GSH and reducing the amount of GSH available to combine with chemotherapeutic agents, thus producing an overall GST-inhibitory effect by sensitizing a cell to chemotherapeutic agents
(PubMed) Labay V, Raz T, Baron D, et al
iii) 1 mol/kg berberine and 100 mol/kg atorvastatin for 1 month (i.v.)
For example, the following options may be used: antithyroid drugs (methimazole and propylthiouracil), radioactive iodine, beta-blockers, and surgery (Wiersinga et al
Oxid Med Cell Longev 2013:956792 Pradhan S, Bonekamp S, Gillen JS et al (2015) Comparison of single voxel brain MRS AT 3T and 7T using 32-channel head coils