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Cell Metab 25(6):1348-1361 e1348

Since Ca 2+ -dependent exocytosis of GLP-1 from L-cells is stimulated by ingested nutrients 17,18,19 , orally administered JWU-A021 might activate intestinal TRPA1 channels so that it replicates the GLP-1 secretagogue effect of such nutrients

If it went through, those peptides could be sold OTC without a prescription, without physician oversight, and without sterility requirements

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