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As an example of its mechanism of action, SAMe supplementation was shown to inhibit DNA demethylase, DNMT1 activity, and demethylation of PS1, a prime gene product involved in amyloidogenesis [143], as discovered in transgenic AD mice

According to some scientists, hydrogen peroxide (H 2 O 2 ) also belongs to this group since it easily penetrates the membranes and in the presence of transition metals (copper or iron) it can be reduced to OH as in the example below (Yu, 1994): Hydroxyl radical is the strongest oxidant generated in biological systems because of its extremely short half-life (Yu, 1994

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there is no established or recommended human or veterinary dose , and this reference does not provide one

Maintains skin brightness and even tone