Summary: B12 injections begin working at a cellular level immediately, though noticeable symptom improvement typically occurs within 4872 hours to several weeks depending on deficiency severity
B12 is absorbed well from the fatty layer, so the vitamin reaches the bloodstream either way
A 2011 systematic review and meta-analysis of nine randomized controlled trials including 19,810 women reported that combined supplementation with vitamins C (1,000 mg/day) and E (400 International Units/day) during pregnancy does not reduce the risk of preeclampsia in women with either low/moderate risk or high risk for this disorder (90)
Energy levels and workout performance should be noted subjectively
[13] Chloramphenicol has been shown to blunt reticulocyte response to cyanocobalamin, while ethanol, colchicine, and nitrous oxide interfere with cobalamin metabolism or utilization, each warranting clinician awareness when evaluating suboptimal treatment outcomes