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It exists in both oxidized (NAD + ) and reduced (NADH) forms, the latter is generated by NAD + accepting high-energy electrons from glycolytic and TCA intermediates and acts as a primary electron donor in ATP synthesis to drive mitochondrial OXPHOS 518

The efficacy of MmDMSA in these animal models was seen through its effects on brain tissue, where it reduced ROS and restored the activity of SOD, GPx, GST and GSH after lead exposure

In a rat model of diabetic cardiomyopathy, TPs significantly improved myocardial function in rats, and cardiomyocyte disorders and hypertrophy were significantly improved (147)

[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Jiang Z.Y., Lu M.C., Xu L.L., Yang T.T., Xi M.Y., Xu X.L., Guo X.K., Zhang X.J., You Q.D., Sun H.P

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