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Supervision ensures that hormonal levels remain balanced

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Normal chow diet (NCD) was obtained from Ssniff Diets

ROS are reactive species that originate from incomplete reduction of oxygen with high chemical reactivity, including the hydroxyl radical, superoxide anion, and hydrogen peroxide ( Decades ago, Otto Warburg put forward that cancer cells depended on glycolysis to support cellular growth even under normoxic conditions (the so-called Warburg effect) ( High-throughput screening performed by the gain or loss-of-function studies in PC cells showed that the differentially expressed genes was partially related to the metabolic process and antioxidant activity

these cytoprotective mechanisms are blunted in hypothyroidism (70, 71)